Free UK delivery on orders over £50Doctor-guided selectionReviewed by a GMC-registered clinicianBuy 3, get 1 free on selected supplementsFree UK delivery on orders over £50Doctor-guided selectionReviewed by a GMC-registered clinicianBuy 3, get 1 free on selected supplements

Why The Wellness recommends this

Curated, not stocked.

Thorne is one of a small number of supplement brands our doctors are genuinely comfortable recommending by name. Their enzyme formulations are broad-spectrum by design — not padded with token additions. We suggest this product for patients who report consistent post-meal bloating or discomfort without a clear dietary trigger, and for those whose digestion has shifted with age or stress. It earns its place through formulation integrity, not marketing.

About this product

Advanced Digestive Enzymes

Thorne Advanced Digestive Enzymes is a multi-enzyme supplement designed to support the breakdown of the main macronutrient groups — proteins, fats, and carbohydrates — as well as difficult-to-digest compounds such as lactose and certain plant fibres. Digestive enzyme blends work by supplementing the body's own pancreatic and intestinal enzymes, which can become insufficient due to age, stress, low stomach acid, or conditions that affect digestive output.

This product suits people who notice bloating, heaviness, or discomfort after meals — particularly after eating rich, fatty, or high-fibre foods. It may also be useful for those with a diagnosed enzyme insufficiency or reduced stomach acid, and for anyone looking to improve nutrient absorption from their diet. It fits naturally into a meal-centred routine and is typically used alongside food rather than on an empty stomach.

Thorne is a brand our clinical team regards as a serious formulation house. Their manufacturing standards are consistently high, and the Advanced Digestive Enzymes product reflects a broad-spectrum approach: rather than targeting a single enzyme category, it provides a range intended to act across the digestive tract. For those whose symptoms are related to specific intolerances, a targeted single-enzyme product may be more appropriate — but for general digestive support, a multi-enzyme blend offers practical flexibility.

What it does

Benefits

  1. 01

    Supports breakdown of proteins, fats, and carbohydrates

  2. 02

    May reduce post-meal bloating and digestive discomfort

  3. 03

    Helps maximise nutrient absorption from meals

  4. 04

    Useful when natural enzyme output is low or declining

  5. 05

    Broad-spectrum coverage across main food groups

Get the most from it

How to use

Take 1–2 capsules with meals. The capsules should be taken at the start of eating so the enzymes are present in the digestive tract alongside the food. Follow the dosage guidance on the packaging for your specific needs.

What's inside

Ingredients

View full ingredient list

Multi-enzyme blend

Common questions

Frequently asked

When should I take digestive enzymes — before, during, or after a meal?

The standard guidance is to take them at the beginning of a meal, so the enzymes are active when food arrives in the stomach and small intestine. Taking them after eating reduces their effectiveness.

Who is most likely to benefit from a digestive enzyme supplement?

People who experience regular bloating, fullness, or discomfort after meals are the typical candidates. They may also suit those with age-related decline in enzyme output, high dietary variety, or diets rich in fat, fibre, or dairy.

Is this suitable if I have a specific food intolerance, such as lactose?

A broad-spectrum blend like this typically includes lactase for lactose digestion, but it is designed as general support rather than a targeted intolerance product. Check the packaging for the specific enzyme profile if you have one particular trigger food.

Can I take this alongside other Thorne supplements or medications?

Digestive enzymes are generally well tolerated alongside other supplements. If you are taking medications — particularly those with enteric coatings or time-release formulations — speak to your pharmacist or doctor before adding enzymes, as they may affect how those medicines are absorbed.

How long before I notice a difference?

Many people notice a reduction in post-meal bloating within the first few days of consistent use with meals. Improvements in broader nutrient absorption are harder to perceive directly and may take longer to observe through markers such as energy or blood nutrient levels.

Doctor-guided care

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THORNE Advanced Digestive Enzymes

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