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Urolithin A is one of the few longevity-focused compounds with genuine human research behind it, and Mitopure is the standardised form that research was largely built on. We chose this product because it pairs that specific ingredient with a liposomal delivery system, addressing one of the practical limitations of oral urolithin A supplementation. For patients interested in mitochondrial health, this is a more substantiated starting point than most options in this space.
About this product
Liposomal Urolithin A
Codeage Liposomal Urolithin A is a supplement delivering Urolithin A via a liposomal format designed to support absorption through the gut wall. Urolithin A is a postbiotic compound — produced when gut bacteria metabolise ellagitannins found in foods such as pomegranates and walnuts. The problem is that fewer than half of adults have the gut microbiome composition to produce meaningful amounts naturally, which is why direct supplementation has attracted serious research interest.
The active here is sourced as Mitopure, a purified, standardised form of Urolithin A that is the most clinically studied version of the compound. Its primary studied mechanism is the activation of mitophagy — the process by which cells clear out damaged mitochondria and replace them with healthier ones. This supports mitochondrial turnover, which declines with age and is closely linked to muscle endurance and cellular energy capacity.
This supplement suits adults focused on longevity, muscle performance, or anyone noticing the kind of gradual decline in energy and physical resilience that tends to track with ageing. It fits naturally into a morning routine alongside other evidence-informed foundational supplements.
Mitopure is the ingredient that earns this product its place here. It is not a generic commodity urolithin A; the standardisation and published research behind it set it apart from most of what is on the market in this category.
What it does
Benefits
- 01
Supports mitochondrial clearance and renewal via mitophagy
- 02
Mitopure: the most clinically studied urolithin A form
- 03
May support muscle endurance and physical resilience with age
- 04
Liposomal format designed to optimise gut absorption
- 05
Useful for adults who cannot produce urolithin A naturally
Get the most from it
How to use
Follow the dosage instructions on the packaging. Liposomal supplements are typically taken in the morning, and can generally be taken with or without food. Consistency over several weeks is usually needed before any effects become noticeable.
What's inside
Ingredients
View full ingredient list
Urolithin A (Mitopure), Liposomal delivery
Common questions
Frequently asked
What is Urolithin A and why can't I just get it from food?
Urolithin A is not found directly in food. It is produced by gut bacteria when they break down ellagitannins from foods like pomegranates and walnuts. Research suggests that a significant proportion of adults lack the specific gut bacteria needed to produce meaningful amounts, making direct supplementation the more reliable route.
What makes Mitopure different from generic Urolithin A?
Mitopure is a purified, standardised form of Urolithin A developed by Amazentis and is the most extensively studied version of the compound in human trials. Generic urolithin A ingredients vary widely in purity and have far less published evidence behind them.
How long before I notice any difference?
Mitophagy and mitochondrial renewal are slow biological processes. Most research protocols run for several weeks at minimum. It is reasonable to allow 8–12 weeks of consistent use before evaluating any change in energy or physical performance.
Is this suitable alongside other supplements or medications?
Urolithin A is not known to interact with common supplements, but if you are on prescription medication — particularly immunosuppressants or drugs with narrow therapeutic windows — it is worth checking with your GP or pharmacist before starting.
Why liposomal delivery specifically?
Liposomal encapsulation wraps the active compound in a phospholipid layer that may improve passage through the gut lining compared to standard oral formats. This is a common approach used to improve the bioavailability of compounds that are otherwise variably absorbed.
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