About this product

Liver Cleanse

A synergistic four-botanical formula combining berberine, milk thistle, burdock root, and chicory root to support bile production, enhance liver detoxification pathways, and protect hepatocytes — the practitioner-grade liver support that addresses the organ processing everything you eat, drink, breathe, and absorb. Your liver performs over 500 functions. It filters every millilitre of blood returning from your digestive tract before it reaches the rest of your body.

It metabolises alcohol, medications, hormones, and environmental chemicals. It produces bile for fat digestion and fat-soluble vitamin absorption. It stores glycogen for energy regulation, synthesises proteins for blood clotting, and processes the ammonia produced by protein metabolism into urea for safe excretion.

No other organ in your body handles this breadth of biochemical responsibility, and no other organ operates under this level of continuous demand. You do not feel your liver working, which is precisely why you do not notice when it is struggling — until fatigue deepens, digestion deteriorates, skin dulls, hormonal balance shifts, and the vague sense that something is off becomes a permanent background hum.

Modern life places unprecedented demands on liver function. Alcohol, processed food, refined sugar, pharmaceutical medications, environmental pollutants, pesticide residues, heavy metals, synthetic hormones, and the metabolic byproducts of chronic stress all funnel through the same hepatic detoxification pathways. Phase I enzymes (primarily cytochrome P450) activate toxins for processing. Phase II enzymes conjugate them for safe excretion. Bile carries the processed waste into the intestines for elimination.

When any stage is overwhelmed — when the volume of incoming substances exceeds the liver's processing capacity — intermediary metabolites accumulate, bile flow stagnates, and the organ that is supposed to protect you from toxicity becomes a bottleneck that perpetuates it. Most people never consider liver support because they associate liver problems with disease. But the gap between optimal liver function and liver disease is wide, and most of the population sits somewhere in that gap, running a detoxification system at reduced capacity without ever crossing a clinical threshold.

Thorne Liver Cleanse addresses this with four botanicals that target complementary aspects of liver function. Berberine HCl (125 mg, from Berberis aristata) stimulates bile production and flow, supports phase I and phase II detoxification enzyme activity, and provides antimicrobial action in the gut that reduces the endotoxin load reaching the liver via the portal vein. Milk Thistle extract (125 mg, standardised to 65% silymarin) is the most extensively researched hepatoprotective botanical in existence — silymarin stabilises liver cell membranes, promotes hepatocyte regeneration, and acts as a potent antioxidant that neutralises free radicals generated during detoxification. Burdock root extract (100 mg) is a traditional cleansing botanical that supports the elimination of metabolic waste products through both hepatic and renal pathways, while providing prebiotic inulin that feeds beneficial gut bacteria. Chicory root extract (100 mg) is a cholagogue — it stimulates the production and release of bile, enhancing the liver's ability to excrete the toxins it has processed and preventing biliary stagnation. Together, these four botanicals create a complete support system: bile production is stimulated, detoxification pathways are enhanced, liver cells are protected, and waste elimination is promoted.

Thorne is NSF Certified for Sport, third-party tested through four rounds of quality verification, and trusted by over 47,000 healthcare practitioners worldwide. Vegetarian capsule. No gluten, dairy, soy, artificial colours, or preservatives. 60 capsules per bottle.

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Take one capsule one to three times daily, or as recommended by your healthcare professional. Begin with one capsule in the evening and increase gradually based on tolerance. Best taken with food. Important: proper intestinal elimination is essential during any liver support protocol. You should be having at least one healthy bowel movement daily before supplementing — if constipation is present, the toxins released into bile may be reabsorbed rather than excreted. Consider adding a fibre supplement if bowel function is suboptimal. Do not use if pregnant, breastfeeding, or trying to conceive. Consult your healthcare professional if taking prescription medications, as berberine can interact with drugs metabolised by cytochrome P450 enzymes. Store in a cool, dry place. Keep out of reach of children. Four botanicals, one purpose — because the organ that detoxifies everything else deserves support of its own.

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