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Thorne is one of a small number of supplement brands our doctors are comfortable recommending without reservation. The citrate-malate form earns its place here specifically — it is absorbed more readily than magnesium oxide, and the malate component adds relevance for energy metabolism beyond simple mineral repletion. For patients whose blood work flags low magnesium or who present with fatigue, cramps, or stress-related depletion, this is a sensible, well-formulated choice.
About this product
Magnesium CitraMate
Magnesium CitraMate by Thorne is a chelated magnesium supplement using citrate-malate, a combination of two organic acid salts chosen for their absorption profile and their role in cellular energy metabolism. Magnesium is an essential mineral involved in over 300 enzymatic reactions — including muscle contraction, nerve signalling, protein synthesis, and the conversion of food into usable energy via the citric acid cycle. The malate component is itself an intermediate in that cycle, making this form particularly relevant for those supporting energy production at a cellular level.
This supplement suits a broad range of people: those with low dietary magnesium intake, individuals experiencing muscle cramps or tension, adults managing fatigue, or those under sustained physical or mental stress — all scenarios where magnesium demand commonly outpaces supply. It fits naturally into a daily nutrition stack, often taken alongside a B-complex or as a standalone mineral top-up confirmed by a blood panel.
Magnesium citrate-malate tends to be better tolerated than oxide forms and less likely to cause the loose stools associated with high-dose magnesium citrate on its own. Thorne is a brand with a strong reputation among practitioners for manufacturing rigour and ingredient quality, and this formulation reflects their preference for well-researched, bioavailable mineral chelates over cheaper inorganic forms.
What it does
Benefits
- 01
Supports cellular energy production via the citric acid cycle
- 02
May ease muscle cramps and tension with regular use
- 03
Well-absorbed chelated form, gentler on the gut
- 04
Useful for adults with high stress or physical training loads
- 05
Backs nerve signalling and protein synthesis daily
Get the most from it
How to use
Take 1 capsule 1 to 3 times daily, or as directed by your practitioner. Magnesium is generally well tolerated with food, which can also reduce the chance of any digestive discomfort at higher doses. If you are using it primarily for sleep support, consider taking one dose in the evening.
What's inside
Ingredients
View full ingredient list
Magnesium Citrate-Malate
Common questions
Frequently asked
How does magnesium citrate-malate differ from standard magnesium citrate?
Magnesium citrate-malate pairs magnesium with both citric and malic acid. Malic acid is a direct intermediate in the citric acid cycle, which cells use to generate energy. This makes the combination particularly relevant for energy metabolism, while the chelated form still offers good bioavailability and gut tolerability.
Will this cause digestive discomfort?
Chelated magnesium forms like citrate-malate are generally better tolerated than magnesium oxide and less likely to cause loose stools than high-dose citrate alone. Taking capsules with food further reduces the risk of any mild digestive sensitivity.
How long before I notice a difference?
This depends on how depleted your magnesium levels are to begin with. Some people notice improvements in muscle tension or sleep quality within one to two weeks of consistent use; others with borderline levels may take longer. A blood test before and after supplementation gives the clearest picture.
Is this suitable to take alongside other supplements or medications?
Magnesium can interact with certain antibiotics, bisphosphonates, and medications for blood pressure or diabetes by affecting absorption or activity. If you are on any prescription medication, check with your GP or pharmacist before adding a magnesium supplement to your routine.
Who might particularly benefit from this supplement?
People with confirmed low magnesium on a blood panel, those in heavy training blocks, individuals under prolonged stress, and adults with diets low in nuts, seeds, and leafy greens are among those most likely to benefit. It is not a substitute for a varied diet, but it is a practical top-up when dietary intake is insufficient.
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