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ChromaDex is not a supplements brand that simply rides a trend — it is the company that commercialised nicotinamide riboside and has continued to fund and publish human research on it. In a category where many products make bold NAD+ claims with little evidence, Niagen stands apart for having peer-reviewed data behind it. We include it because the formulation is clean, the ingredient is traceable, and the science is real.
About this product
Tru Niagen - 300 mg
Tru Niagen is a nicotinamide riboside (NR) supplement from ChromaDex, the company that holds the foundational patents on NR as a distinct form of vitamin B3. NR is a precursor to NAD+, a coenzyme involved in cellular energy metabolism, DNA repair, and the activity of sirtuins — proteins studied for their role in healthy ageing. NAD+ levels decline naturally with age, and supplementing with a precursor such as NR is one of the more researched strategies for supporting those levels.
This formulation delivers 300 mg of nicotinamide riboside per capsule. It suits people who want to address age-related cellular decline, those in demanding physical or cognitive routines, and anyone whose clinician has flagged NAD+ support as relevant to their health picture. It is not a quick-fix; consistent daily use over weeks is how most people approach it.
ChromaDex uses a patented form of NR called Niagen, which has been the subject of peer-reviewed human studies examining its ability to raise blood NAD+ levels. The ingredient has a more substantial evidence base than many NAD+ precursors on the market, which is a meaningful distinction in a category full of loosely substantiated products. For those serious about cellular health and longevity science, this is one of the more credible starting points.
What it does
Benefits
- 01
Supports NAD+ levels, which decline naturally with age
- 02
May assist cellular energy metabolism day to day
- 03
Studied for a role in healthy ageing via sirtuin activity
- 04
Relevant for those in demanding physical or cognitive routines
- 05
A well-researched NR source backed by peer-reviewed studies
Get the most from it
How to use
Take one capsule daily. It may be taken with or without food. Consistency matters more than timing — pick a time of day you can stick to and maintain it for several weeks before assessing any effect.
What's inside
Ingredients
View full ingredient list
Nicotinamide Riboside 300mg
Common questions
Frequently asked
What is nicotinamide riboside and how does it differ from niacin?
Nicotinamide riboside (NR) is a form of vitamin B3, as is niacin. The key difference is the pathway each takes to raise NAD+ levels. NR converts to NAD+ via a distinct enzymatic route and, unlike high-dose niacin, is not associated with the skin flushing that many people find uncomfortable.
How long before I notice any difference?
NAD+ precursors tend to work gradually at the cellular level rather than producing noticeable day-one effects. Most human studies run for several weeks. It is reasonable to commit to daily use for four to eight weeks before drawing conclusions, and some people track progress alongside a blood panel.
Can I take this alongside other supplements or medications?
NR is generally well tolerated, but if you are on any prescription medication — particularly those affecting liver metabolism — it is worth checking with your GP or clinician before adding it. As with any supplement, do not exceed the recommended dose without professional guidance.
Is this suitable for vegetarians or vegans?
Check the packaging for full excipient and capsule details, as we cannot confirm the shell composition from the information available here.
Does taking more than one capsule increase the benefit?
Some individuals take higher amounts under clinical guidance, but the established daily dose for this product is one capsule. Do not adjust the dose without speaking to a clinician — more is not automatically better, and the evidence base is built around studied amounts.
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