Tru Niagen PRO 1000mg

Name: Tru Niagen PRO 1000mg
Brand: Chromadex
SKU: product-0435
Price: 95.00 GBP
Availability: InStock
Rating: 4.9 (10 reviews)

£95.00

Tru Niagen PRO 1000mg is a high-dose nicotinamide riboside (NR) supplement from ChromaDex, the company that pioneered and holds the foundational patents on NR as a consumer ingredient.

Raises NAD+ levels via a direct, well-studied B3 precursor
Supports mitochondrial energy production at the cellular level
Relevant for age-related decline in NAD+ availability
High-dose format for those seeking a meaningful NR intake
Sourced from the originator brand behind the NIAGEN ingredient

4.9 (10 reflections)

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ChromadexTru Niagen PRO 1000mg

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about this product.

Tru Niagen PRO 1000mg is a high-dose nicotinamide riboside (NR) supplement from ChromaDex, the company that pioneered and holds the foundational patents on NR as a consumer ingredient. Nicotinamide riboside is a form of vitamin B3 that serves as a direct precursor to NAD+, a coenzyme central to cellular energy metabolism, DNA repair, and mitochondrial function. NAD+ levels decline measurably with age, and NR is one of the more studied oral strategies for raising them.

This formulation is suited to those who have made an informed decision to support NAD+ levels at a meaningful dose — whether for general longevity interest, during periods of physiological stress, or alongside medical guidance for conditions where mitochondrial support is relevant. At this dose, it sits at the higher end of the NR range available without prescription.

ChromaDex supplies NR as NIAGEN to many other supplement brands, so sourcing it direct from ChromaDex means you are working with the originator of the ingredient. The science around NR continues to mature; human trials have consistently shown that oral NR raises whole-blood NAD+ levels, though the downstream health implications of this are still being studied. This is a supplement to sit alongside a sensible diet and lifestyle, not a replacement for understanding your baseline through blood testing.

frequently asked.

How is nicotinamide riboside different from regular niacin or NMN?

Nicotinamide riboside (NR), niacin, and NMN are all NAD+ precursors but follow different biochemical pathways to get there. NR is generally better tolerated than niacin (which can cause flushing) and has a more established human trial record than NMN at this stage. They are not interchangeable, though they share the same end goal of raising NAD+.

How long before I notice a difference?

Human studies have shown measurable increases in blood NAD+ levels within two to four weeks of consistent NR supplementation. Subjective changes — if any — tend to be subtle; this is not a supplement with an immediate, noticeable effect for most people. Think of it as a long-term investment rather than a short-term fix.

Is it safe to take alongside other supplements or medications?

NR is generally considered well-tolerated, but if you are taking medications — particularly those affecting DNA repair pathways or cancer treatments — speak to your doctor before adding a high-dose NAD+ precursor. As with any supplement at this dose, a clinical conversation is worthwhile if you have an underlying condition.

Who is this not suitable for?

Pregnant or breastfeeding individuals should avoid NR supplements unless advised otherwise by a clinician, as safety data in these groups is limited. Those with a history of certain cancers should consult their oncologist, given that NAD+ plays a role in cell proliferation pathways.

Why is Tru Niagen more expensive than other NR supplements?

ChromaDex manufactures NIAGEN, the NR ingredient that many competing brands actually buy from them and repackage. Purchasing Tru Niagen PRO means you are buying directly from the source. The price also reflects the higher dose format — check the per-milligram cost against alternatives before assuming it is less competitive.

Customer reflections

Overall sentiment

4.910 reflections

1 – 6 of 10 reflections

QQVerified Buyer

The first adrenal support that made a quick difference.

4 days ago

Gentle on a sensitive stomach, and I feel like myself again. I had tried two other glandulars before this and neither sat right.

MRVerified Buyer

Steadier mornings within a fortnight.

1 week ago

I was sceptical about glandulars, but my mid-afternoon crash has genuinely eased. One capsule with breakfast and I forget about it.

ALVerified Buyer

Subtle, but real.

2 weeks ago

Not a stimulant, which is exactly what I wanted. It took about ten days, then I realised I wasn’t dreading the afternoon any more.

SKVerified Buyer

My clinician recommended it.

3 weeks ago

Bought after a blood panel flagged a flat cortisol curve. Easy to take, no jitters, and the sourcing is refreshingly transparent.

TPVerified Buyer

Recovery feels faster.

1 month ago

Training hard through a stressful stretch and this has helped me bounce back between sessions. Already on my second bottle.

DVVerified Buyer

Does what it says.

1 month ago

No frills, one ingredient, a sensible dose. I appreciate that it is designed to be used for a season rather than forever.

Tru Niagen PRO 1000mg

about this product.

how to take it

frequently asked.

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Customer reflections